Semaglutide – 10mg*10 vials
$80.00
Semaglutide is a highly potent, long-acting agonist of the GLP-1 (glucagon-like peptide-1) receptor, specifically engineered for metabolic and endocrine research. Known for its exceptional stability and extended half-life, this peptide is the gold standard for studying glycemic control, appetite regulation, and cellular insulin response. Each vial is vacuum-sealed and guaranteed at 99% purity, providing researchers with a reliable, pharmaceutical-grade reagent for sensitive experimental models.
Out of stock
Description
Overview of Semaglutide
Semaglutide is a synthetic 31-amino acid peptide analog of human GLP-1. It is distinguished from native GLP-1 by three key modifications: amino acid substitutions at positions 8 and 34, and the attachment of a C18 fatty diacid side chain at position 26. These structural optimizations allow the compound to resist degradation by the enzyme DPP-4 and bind strongly to albumin, resulting in a prolonged duration of action that is ideal for longitudinal research studies.
Primary Research Applications
As a selective GLP-1 receptor agonist, Semaglutide is an essential tool for exploring:
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Incretin System Dynamics: Analyzing how GLP-1 analogs stimulate glucose-dependent insulin secretion and inhibit glucagon release.
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Gastric Motility and Satiety: Investigating the central and peripheral mechanisms that delay gastric emptying and modulate hunger signals in the hypothalamus.
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Cardiovascular and Neuroprotective Studies: Researching the secondary effects of GLP-1 activation on cardiac inflammation, vascular health, and neuronal survival in neurodegenerative models.
