IGF-DES - 2mg

IGF-DES – 2mg

$80.00

IGF-1 DES (1-3) is an ultra-potent, truncated analog of Insulin-like Growth Factor-1. By removing the first three amino acids (Glu-Pro-Gly) from the N-terminus, the peptide’s affinity for IGF-binding proteins (IGFBPs) is virtually eliminated. This results in a compound that is approximately 10 times more potent than endogenous IGF-1 at stimulating cellular growth and glucose uptake. Each 2mg vial is vacuum-sealed and guaranteed at 99% purity, making it a premier tool for researching site-specific hyperplasia and rapid tissue remodeling.

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Description

Overview of IGF-1 DES

IGF-1 DES is a 67-amino acid version of the IGF-1 molecule. While the “Long R3” version of IGF-1 is designed for a long systemic half-life, IGF-1 DES is designed for high-intensity, localized activity. Because it does not bind to IGFBPs, it is immediately “bioavailable” to the IGF-1 receptors (IGF-1R). This lack of binding proteins, combined with a very short half-life (approximately 20–30 minutes), makes it the primary subject for researchers studying localized cellular responses and the “pump” effect in musculoskeletal tissues.

 

Primary Research Applications

This 2mg formulation is specifically utilized in molecular and physiological research to explore:

  • Site-Specific Hyperplasia: Investigating the proliferation of new muscle cells (satellite cell activation) within specific targeted tissue zones.

  • Lactic Acid Receptor Interaction: Researching the unique ability of IGF-1 DES to bind to receptors that have been “deformed” by lactic acid, making it highly effective in studying recovery in post-exertion environments.

  • Glucose Transport and Metabolism: Analyzing the peptide’s ability to facilitate rapid glucose uptake into cells, potentially bypassing or augmenting the insulin signaling pathway.

  • Neurological Regeneration: Studying the peptide’s impact on the repair of localized nerve damage and its role in neuroplasticity within the central nervous system.

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